A Novel Lectin Was Isolated by the Research Team of Jinchi Biotech Ltd. (JBL)
Lately, Andrias Davidianus Lectin (ADL) was isolated successfully from the body-surface mucus of Andrias Davidianus (Giant Salamander) by JBL Research Team who had done 3 years of research on purification of a secreted lectin from Andrias Davidianus skin and its antibacterial activity. In August of 2014, the research paper of ADL-related research achievement was published in ‘Comparative Biochemistry and Physiology, Part C, DOI: 10.1016/j.cbpc.2014.08.008’.
ADL is very important to the body-surface immunity of Andrias Davidianus. ADL is a 17 kDa carbohydrate-binding protein, and it contains 2 identical 8.5 kDa subunits. The discovery and application of the lectin have great significance for Andrias Davidianus breeding and disease prevention.
Lectins are considered to be non enzymatic and non immune proteins or multivalent carbohydrate-binding protein, widely exist in animals (including amphibians), plants and microorganisms. Isolation and identification of lectins are particularly important in the study on pathogenesis process of microbial related.